Assessment of neuroendocrine dysfunction following traumatic brain injury.

A screening protocol adapted for selected patients at risk for endocrine problems is described, and physicians should be aware of the importance of neuroendocrine dysfunction following TBI. Posttraumatic neuroendocrine pathology may be a clinically significant complication following traumatic brain injury TBI. Metabolic abnormalities are described after TBI in two cases. A 21 year old male injured in a motor vehicle accident admitted in a minimally responsive condition presented with fluctuating high sodium levels, undetectable serum testosterone, and depressed cortisol and thyroid function. Imaging revealed near complete avulsion of the pituitary stalk leading to panhypopituitarism. A 38 year old male admitted for occipital skull fractures and brain contusions presented with hypona tremia and low serum testosterone. Both patients required hormonal replacement and correction of electrolyte abnormalities. A screening protocol adapted for selected patients at risk for endocrine problems is described. While neuroendocrine screening is not advocated in all TBI patients, physicians should be aware of the importance of neuroendocrine dysfunction following TBI.

Post Head Injury Endocrine Complications Treatment & Management: Surgical Intervention, Consultations, Other Treatment

Metabolic disorders on cognitive dysfunction after traumatic brain injury: Trends in Endocrinology & Metabolism

Traumatic Brain Injury: A Clinician's Guide to Diagnosis, Management, and Rehabilitation

Traumatic brain injury: Pathology review: Video

Clinical algorithm for assessment of DI following TBI. DI diabetes

Progress Toward a Multiomic Understanding of Traumatic Brain Injury: A Review - Philip A Kocheril, Shepard C Moore, Kiersten D Lenz, Harshini Mukundan, Laura M Lilley, 2022

Neuroendocrine disorders after traumatic brain injury

Endocrine Dysfunction After Traumatic Brain Injury: An Ignored Clinical Syndrome?

JCM, Free Full-Text

JCM, Free Full-Text

Frontiers Iron Metabolism Disorders for Cognitive Dysfunction After Mild Traumatic Brain Injury

Endocrine Dysfunction After Traumatic Brain Injury: An Ignored Clinical Syndrome?