Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease - Ruđer Bošković Institute

The goal of this project is to elucidate the molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease (NPC). We will investigate the role of protease BACE1, the key Alzheimer's disease (AD) enzyme, in the pathogenesis of NPC disease. We hope that our findings will elucidate BACE1 as a novel target for treating/ameliorating NPC disease.

Modeling Brain Pathology of Niemann‐Pick Disease Type C Using

IJMS, Free Full-Text

Psychiatric and Cognitive Symptoms Associated with Niemann-Pick

PDF] Niemann-Pick Type C Disease—Pathophysiology and Future

PDF] Molecular mechanisms of neurodegeneration in Alzheimer's

Martina MALNAR, PostDoc, PhD

Solving neurodegeneration: common mechanisms and strategies for

PDF] Molecular mechanisms of neurodegeneration in Alzheimer's

PDF) Impaired Retromer Function in Niemann-Pick Type C Disease Is

Molecular Mechanisms of Neurodegeneration: Neurodegenerative

Niemann-Pick disease type C

Niemann-Pick-C desease - CERMO-FC

Marko KOSICEK, PhD, Ruđer Bošković Institute, Zagreb